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Jeffrey
M. Voigt, Ph.D.
Associate Professor
Department of Pharmaceutical Sciences
(o) 518.694.7308
Education:
Ph.D., Pharmacology, University of Iowa
Courses Taught at ACP:
Biochemistry, Pharmacology, Seminar, Principles of
Analytical Techniques
Awards:
Named 2006-07 ACP Professional Teacher of the Year
Research Interests:
VDUP-1 (TBP-2) is a protein whose expression is decreased in tumors and increased following treatment with Vitamin D. VDUP-1 functions as an inhibitor of thioredoxin, which interacts with a number of transcription factors. Dr. Voigt is currently investigating the role of VDUP-1 in regulation of transcription factor activity and cell proliferation/differentiation in different cell types.
Recent Publications:
Mandalaywala, N.V., Chang, S., Snyder, R.S., Levendusky, M.C., Voigt, J.M., and Dearborn Jr., R.E. (2008) The tumor suppressor, vitamin D3 up-regulated protein 1 (VDUP1), functions downstream of REPO during Drosophila gliogenesis. Dev. Biol. 315:489-504.
Colby, H.D., Nowak, D.M., Longhurst, P.A., Zhang, X., Hayes, J.R., and Voigt, J.M. (2001) Bufuralol metabolism by guinea pig adrenal and hepatic microsomes. Pharmacology 62:229-233.
Colby, H.D., Huang, Y., Jiang, Q., and Voigt, J.M. (2000) Bimodal expression of CYP2D16 in the guinea pig adrenal cortex. Pharmacology 61:78-82.
Yuan, B.B., Tchao, R., Voigt, J.M., and Colby, H.D. (1998) Effects of ACTH administration on functional zonation of the guinea pig adrenal cortex. Mol. Cell. Endocrinol. 146:129-136.
Yang, X., Young, L.H., and Voigt, J.M. (1998) Expression of a vitamin D-inducible gene in untreated rat mammary tissue and MNU-treated mammary tissue. Breast Cancer Res. Trt. 48:33-44.
Young, L.Y., Yang, X., and Voigt, J.M. (1996) Alteration of gene expression in rat mammary tumors induced by N-methyl-N-nitrosourea. Molecular Carcinogenesis 15:251-260.